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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYN
All Species:
18.18
Human Site:
S457
Identified Species:
40
UniProt:
P07948
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07948
NP_001104567.1
512
58574
S457
A
D
V
M
T
A
L
S
Q
G
Y
R
M
P
R
Chimpanzee
Pan troglodytes
XP_514571
635
71442
E580
P
E
V
I
R
A
L
E
R
G
Y
R
M
P
R
Rhesus Macaque
Macaca mulatta
XP_001087049
602
68092
S547
A
D
V
M
T
A
L
S
Q
G
Y
R
M
P
R
Dog
Lupus familis
XP_535078
512
58757
S457
A
D
V
M
T
A
L
S
Q
G
Y
R
M
P
R
Cat
Felis silvestris
Mouse
Mus musculus
P25911
512
58794
S457
A
D
V
M
S
A
L
S
Q
G
Y
R
M
P
R
Rat
Rattus norvegicus
Q07014
512
58642
S457
A
D
V
M
T
A
L
S
Q
G
Y
R
M
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514812
514
58948
Q459
A
D
V
M
T
A
L
Q
Q
G
Y
R
M
P
R
Chicken
Gallus gallus
P42683
508
58121
E453
P
E
V
I
Q
N
L
E
R
G
Y
R
M
P
Q
Frog
Xenopus laevis
P10936
537
60339
E480
R
E
V
L
E
Q
V
E
R
G
Y
R
M
P
C
Zebra Danio
Brachydanio rerio
NP_001004543
510
58239
Q455
S
E
V
M
S
S
V
Q
R
G
Y
R
M
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
E460
A
E
V
L
T
Q
V
E
H
G
Y
R
M
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.3
80
97
N.A.
96
96
N.A.
93.1
63
56.7
76.3
N.A.
51.4
N.A.
N.A.
N.A.
Protein Similarity:
100
68.5
81.5
99.2
N.A.
98.8
98.8
N.A.
96.6
77.7
72
86.9
N.A.
69.2
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
93.3
100
N.A.
93.3
46.6
40
53.3
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
93.3
73.3
66.6
93.3
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
0
0
0
0
64
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
46
0
0
10
0
0
37
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
19
0
0
73
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
64
0
0
0
0
0
0
0
0
100
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
10
19
0
19
55
0
0
0
0
0
19
% Q
% Arg:
10
0
0
0
10
0
0
0
37
0
0
100
0
0
73
% R
% Ser:
10
0
0
0
19
10
0
46
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
100
0
0
0
28
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _